Projects

Ing. Alexandra Zahradníková, DrSc.
Chief Research Fellow

International

Finished
  • RyRinHeart - Discovery of Ryanodine Receptor Inhibitors for Heart Diseases
    Program: Bilateral - other
    Duration: 1. 1. 2020 – 31. 12. 2022

National

Current
  • Mitochondrial disease in heart failure
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • Mutations associated with Wolfram syndrome: alternative signaling pathways for calcium and mitochondrial physiology
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
Finished
  • Dyad remodelling in cardiomyocytes in experimental therapy of failing heart
    Program: VEGA
    Duration: 1. 1. 2021 – 31. 12. 2024
  • Dominant mutations in Wolfram syndrome: different mechanism to the recessive ones?
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Regulation of Pericellular Proteolysis: From Molecular Mechanisms To Novel Immune Cell Subsets and Therapeutic Tools
    Program: SRDA
    Duration: 1. 7. 2017 – 31. 12. 2021
  • Diastolic function of the ryanodine receptor and generation of arrhythmogenic calcium waves
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • Cytoarchitecture of calcium signalling of cardiac myocytes in development of myocardial hypertrophy
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2019