Projects

RNDr. Alexandra Zahradníková, ml., PhD.
senior research fellow

International

Current
  • European Network for Sigma-1 Receptor as a Therapeutic Opportunity
    Program: COST
    Duration: 25. 10. 2024 – 24. 10. 2028
Finished
  • Metabolic therapy of heart failure: which role for B vitamins
    Program: ERANET
    Duration: 1. 4. 2020 – 31. 3. 2024
  • A4L_ACTIONS Interorganellar communication malfunction in rare diseases – implication for heart contractility
    Program: Other
    Duration: 1. 3. 2023 – 29. 2. 2024
  • RyRinHeart - Discovery of Ryanodine Receptor Inhibitors for Heart Diseases
    Program: Bilateral - other
    Duration: 1. 1. 2020 – 31. 12. 2022

National

Current
  • Molecular mechanisms implicated in corticosteroid-monoamine interaction in stress-related cardio- and neuropathologies
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • Therapeutic role of selective ChE inhibition in heart failure
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • Mitochondrial disease in heart failure
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • Mutations associated with Wolfram syndrome: alternative signaling pathways for calcium and mitochondrial physiology
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
Finished
  • Dyad remodelling in cardiomyocytes in experimental therapy of failing heart
    Program: VEGA
    Duration: 1. 1. 2021 – 31. 12. 2024
  • Mechanisms of skeletal muscle adaptation to regular exercise in patients with chronic metabolic and inflammatory disease
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Regulation of Pericellular Proteolysis: From Molecular Mechanisms To Novel Immune Cell Subsets and Therapeutic Tools
    Program: SRDA
    Duration: 1. 7. 2017 – 31. 12. 2021
  • Diastolic function of the ryanodine receptor and generation of arrhythmogenic calcium waves
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • Cytoarchitecture of calcium signalling of cardiac myocytes in development of myocardial hypertrophy
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2019