Projects

RNDr. Michal Cagalinec, PhD.
Principal Investigator; Head of the Dept. of Cellular Cardiology

International

Current
  • European Network for Sigma-1 Receptor as a Therapeutic Opportunity
    Program: COST
    Duration: 25. 10. 2024 – 24. 10. 2028
Finished
  • A4L_ACTIONS Interorganellar communication malfunction in rare diseases – implication for heart contractility
    Program: Other
    Duration: 1. 3. 2023 – 29. 2. 2024
  • RyRinHeart - Discovery of Ryanodine Receptor Inhibitors for Heart Diseases
    Program: Bilateral - other
    Duration: 1. 1. 2020 – 31. 12. 2022
  • The link between PDS and mitochondria in epileptogenesis
    Program: Other
    Duration: 1. 1. 2016 – 30. 6. 2018

National

Current
  • Genetic causes of rare inherited metabolic diseases with emphasis on functional studies of novel variants
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • Molecular mechanisms implicated in corticosteroid-monoamine interaction in stress-related cardio- and neuropathologies
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • The role of GPR180 in regulation of pancreatic beta cell function and pathogenesis of diabetes
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Mitochondrial disease in heart failure
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • Mutations associated with Wolfram syndrome: alternative signaling pathways for calcium and mitochondrial physiology
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
Finished
  • Dyad remodelling in cardiomyocytes in experimental therapy of failing heart
    Program: VEGA
    Duration: 1. 1. 2021 – 31. 12. 2024
  • Dominant mutations in Wolfram syndrome: different mechanism to the recessive ones?
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Diastolic function of the ryanodine receptor and generation of arrhythmogenic calcium waves
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • Cytoarchitecture of calcium signalling of cardiac myocytes in development of myocardial hypertrophy
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2019
  • Mitochondrial dynamics and morphology in transgenic model of Wolfram syndrome: emerging role for heart protection
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2018
  • Mitochondria-endoplasmic reticulum functional interplay in Wolfram Syndrome: emerging role for heart and brain protection
    Program: SASPRO
    Duration: 1. 3. 2015 – 31. 12. 2018
Employees