Projects

prof. PharmDr. Daniela Ježová, DrSc.

International

Current
  • Reward-stress interactions as neurobiological substrate for resilience and vulnerability in mental health and depression: A translational large-scale project
    Program: ERANET
    Duration: 1. 1. 2024 – 31. 12. 2026
  • Genome Editing to Treat Humans Diseases
    Program: COST
    Duration: 15. 9. 2022 – 14. 9. 2026
Finished
  • The importance of brain-gut interaction in the development of posttraumatic stress disorder based upon preclinical studies
    Program: Mobility
    Duration: 1. 1. 2023 – 31. 12. 2024
  • UNveiling the MEchanism(s) underlying the switch to mania during antidepressant treatment: The role of glutamate
    Program: ERANET
    Duration: 1. 7. 2019 – 31. 1. 2024
  • The role of specific cell-types of the median raphe in behavior: the excitatory vesicular glutamate transporter 3 and the inhibitory GABA
    Program: Inter-academic agreement
    Duration: 1. 1. 2019 – 30. 12. 2022
  • Effects of vortioxetine in the tryptophan-depletion model of SSRI-resistant depression in female rats
    Program: Other
    Duration: 1. 7. 2014 – 31. 12. 2018
  • Characterization of the molecular mechanisms that modulate GPM6A-­induced filopodium formation during chronic stress exposure
    Program: Inter-academic agreement
    Duration: 1. 1. 2017 – 31. 12. 2018
  • Vesicular glutamate transporter 3 knockout mice and changes in gene expression of the transporter: relation to stress hormones, behavior and animal models of mood disorders
    Program: Inter-academic agreement
    Duration: 1. 1. 2016 – 31. 12. 2018
  • Developing a rat model of depression based on tryptophan deficiency
    Program: Bilateral - other
    Duration: 1. 5. 2011 – 31. 12. 2017
  • Aldosterone and Mineralocorticoid Receptor
    Program: COST
    Duration: 23. 11. 2016 – 30. 11. 2017
  • Chronic stress impact on neuronal membrane glycoprotein M6a: pathway and regulation analysis
    Program: Inter-academic agreement
    Duration: 1. 1. 2013 – 31. 12. 2015
  • Specific features of stress regulation during the perinatal period
    Program: Other
    Duration: 1. 1. 2013 – 31. 12. 2014
  • Interaction of nutrients and oxytocin in modulating neuroendocrine, metabolic and cardiovascular functions.
    Program: Bilateral - other
    Duration: 1. 5. 2011 – 1. 5. 2013
  • Developing a rat model of depression based on tryptophan deficiency
    Program: Bilateral - other
    Duration: 1. 5. 2011 – 1. 5. 2012
  • The action program Austria – Slovakia, cooperation in science and education – study and research mobility
    Program: Bilateral - other
    Duration: 1. 1. 2010 – 30. 6. 2010
  • Educational outcome of collaborative studies within an AUstrian-Slovak research unit focused on evaluating mental and cardiovascular stress.
    Program: Bilateral - other
    Duration: 1. 10. 2008 – 30. 11. 2009
  • Environmental stimuli and neuronal plasticity
    Program: Inter-governmental agreement
    Duration: 1. 1. 2005 – 31. 12. 2006

National

Current
  • CARDIOvascular protection mediated by alfa1AMPK against metabolic syndrome-mediated ENdothelial Dysfunction – identifying new risk factors
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • Coping with psychosocial stress situations in patients with depressive disorder in relation to age and unravelling the mechanisms involved
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Enhancement of endocannabinoid signaling as a promising target for the treatment of stress-related psychiatric disorders
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
Finished
  • Activation of the VGF/BDNF/TrkB pathway by synthetic mRNA encapsulated in polyplex nanoparticles: effects on neural excitability, neuroplasticity and animal behavior
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2025
  • Bridge between the mental state and neuroendocrine function of mother and her child: the mechanisms involved
    Program: SRDA
    Duration: 1. 7. 2019 – 30. 6. 2023
  • Interrelationships between endocrine and mental characteristics of women in reproductive age
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Identification of psychological and somatic markers in relation to vulnerability to stress and analysis of the effectiveness of psychological interventions
    Program: SRDA
    Duration: 1. 8. 2018 – 31. 7. 2022
  • Mineralocorticoid receptors in novel target tissues – pathophysiological relevance and underlying mechanisms
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2021
  • Molecular bases of depressive disorders in children and adolescents, effect of omega-3 fatty acids and oxidative stress
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Prenatal and postnatal effects of delta and mu opioid receptor ligands on the hippocampal development and function.
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 10. 2020
  • Interaction of nitrergic, neurotrophic and endocrine signaling in the etiopathogenesis of schizophrenia
    Program: SRDA
    Duration: 1. 7. 2015 – 30. 6. 2019
  • The clinical significance of the relationship between aldosterone and depression and the regulatory mechanisms involved
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
  • Cognitive, personal and psychophysiological factors of the stress in the context of the relationship between anxiety and allergies and their optimalisation
    Program: SRDA
    Duration: 1. 10. 2013 – 30. 9. 2017
  • Mechanisms of atypical effects of hormones
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • University Biomedical Research Park Bratislava
    Program: EU Structural Funds Research & Development
    Duration: 1. 7. 2013 – 31. 12. 2015
  • Centre of Excellence for the study of metabolic aspects of development, diagnostics and treatment of malignancies
    Program:
    Duration: 4. 8. 2011 – 30. 6. 2015
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    Program:
    Duration: 1. 6. 2011 – 31. 12. 2014
  • Center of excellence for the study of metabolic aspects of development, diagnostics and treatment of cancer diseases
    Program:
    Duration: 1. 7. 2011 – 31. 12. 2014
  • Interaction of mental, cardiovascular, neuroendocrine and metabolic factors: from animal models toclinical applications
    Program: SRDA
    Duration: 1. 5. 2011 – 31. 12. 2014
  • Atypical effects of hormones
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 12. 2013
  • Neuroendocrine correlates of anxiety
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Education of young specialists in the field of the neurobiological basis of mental disorders
    Program: SRDA
    Duration: 1. 11. 2006 – 30. 11. 2009
  • Health of inhabitants of Bratislava region – contribution to better coping with stress based on results of top research
    Program:
    Duration: 1. 10. 2005 – 30. 9. 2008
  • Neuroendocrine mechanisms related to mental state and to the action of psychotropic drugs
    Program: VEGA
    Duration: 1. 1. 2005 – 1. 12. 2007
Employees