Projects

Mgr. Soňa Scsuková, CSc.
senior researcher

National

Current
  • Assessment of protective action of selected phytochemicals against metal nanoparticle-induced neurotoxicity using in vitro cell models
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Biologically relevant mixtures of endocrine disruptors: effects on in vitro models of ovarian intrafollicular processes and ovarian cancer cell lines
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Investigation of new molecular regulatory mechanisms of selected biologically active 4H-pyran-4-ones in relation to their prospective applicability in human oncology
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2026
Finished
  • Molecular mechanisms of trialkyl-/triaryltin isothiocyanates\' and carboxylates\' antitumour properties - novel ligands of nuclear retinoid X receptors in rat mammary gland carcinomas and human tumour cell lines
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2025
  • Impact of selected metal nanoparticles on steroidogenesis: comparison of in vitro cell models
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2022
  • The safety of use of analogs of the endocrine disruptor Bisphenol A: evaluation of effects on in vitro models of ovarian intrafollicular processes and and ovarian cancer cell lines
    Program: VEGA
    Duration: 1. 1. 2018 – 31. 12. 2020
  • Novel synergistic antitumour properties ofnuclear retinoid X receptor (RXR) agonists as a consequence of the conditional RXR-RAR heterodimer formation in human breast cancer cells
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Potential risk of metal and metal oxide nanoparticles used for biomedical applications: focus on reproductive and immune systems and brain
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Investigation of anatomical-functional differences between the effects of aripiprazole and quetiapine, atypical antipsychotics with simiral terapeutic indications, but different impact on brain dopaminergic receptors, in experimental animals
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Characterization of effects of neonatal exposure to nanoparticles in selected brain structures and reproductiveorgans in adult and infantile female rats
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • Acute and reproductive toxicity of selected types of nanoparticles: an in vivtro model
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • Antitumour versus disruption effects of biologically active triaryl-/trialkyl-organometal ligands of retinoid X receptors in tissue cultures of tumour cells
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • Biosafety of therapeutically and commercially used nanoparticles: focus on reproductive and immune system, oxidative status and prevention of potential risk
    Program: SRDA
    Duration: 1. 7. 2012 – 31. 12. 2015
  • Testing and assessment of reproductive toxicity of nanoparticles in in vitro models.
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 12. 2013
  • Cooperation between endocrine and paracrine factors in regulation of ovarian intrafollicular processes
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Effect of binary mixtures of xenoestrogens on ovarian intrafollicula processes
    Program: VEGA
    Duration: 1. 1. 2006 – 1. 12. 2007
Employees