Projects

Mgr. Jozef Ukropec, DrSc.
head of the Department of Metabolic Disease Research

International

Current
  • Alzheimer\'s Disease Diagnostics Innovation and Translation to Clinical Practice in Central Europe
    Program: Horizon Europe
    Duration: 1. 1. 2023 – 31. 12. 2026
Finished
  • DE-PASS Determinants of Physical Activities in Settings
    Program: COST
    Duration: 22. 7. 2020 – 25. 4. 2025
  • Myokines and metabolically active molecules in the pathogenesis of idiopathic inflammatory myopathies
    Program: Other
    Duration: 1. 5. 2021 – 31. 12. 2024
  • Novel strategies aimed to improve the physical fitness, clinical symptoms and quality of life in the early-stage Parkinson’s disease patients: Regular exercise training and carnosine
    Program: Bilateral - other
    Duration: 1. 1. 2019 – 31. 12. 2021
  • Mitochondrial mapping: Evolution - Age - Gender - Lifestyle - Environment
    Program: COST
    Duration: 1. 1. 2017 – 28. 2. 2021
  • High-field MRS, a tool to estimate the tissue-specific metabolic state reflecting thyroid hormone activity in vivo: validation of the “virtual biopsy” clinical relevance
    Program: Bilateral - other
    Duration: 1. 1. 2018 – 31. 12. 2019
  • Skeletal muscle metabolic abnormalities in patients with idiopathic inflammatory myopathies
    Program: Bilateral - other
    Duration: 1. 1. 2016 – 31. 12. 2019
  • Skeletal muscle as a mediator of beneficial effects of regular exercise on cognitive functions and metabolism in patients with Alzheimer\'s disease: the role of muscle myokines and microRNAs.
    Program: Bilateral - other
    Duration: 1. 1. 2014 – 31. 12. 2016
  • Effect of exercise on pathophysiology of type 2 diabetes: Focus on magnetic resonance imaging and spectroscopy in skeletal muscle
    Program: Bilateral - other
    Duration: 15. 1. 2014 – 30. 6. 2015
  • Metabolic health and muscle secretory profile in aerobic and resistance trained obese pre-diabetic individuals
    Program: Multilateral - other
    Duration: 15. 2. 2010 – 14. 2. 2013
  • Pfizer Global Investigator Initiated Research Grant s názvom „The Effect of a Long-Term Growth Hormone Supplementation on the Whole-Body Metabolic Characteristics and Adipose Tissue Phenotype in Growth Hormone Deficient Adults: the 5-yr follow-up
    Program: Bilateral - other
    Duration: 1. 1. 2011 – 31. 1. 2013
  • Adipose tissue and skeletal muscle plasticity in metabolic health and in insulin resistance
    Program: Multilateral - other
    Duration: 25. 1. 2010 – 24. 1. 2013
  • Bioactive food components, mitochondrial function and health
    Program: COST
    Duration: 1. 5. 2007 – 31. 5. 2011

National

Current
  • Molecular mediators of the response to complex lifestyle intervention in patients with obesity: Regulation of metabolic flexibility in vitro and in vivo
    Program: SRDA
    Duration: 1. 7. 2024 – 30. 6. 2028
  • Extracellular vesicles a tool integrating adaptive response to exercise: in vitro and in vivo studies
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Elucidating the molecular mechanisms and metabolic regulation of substrate cycles
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • Lactate, a metabolic signal and energy source for alternative thermogenesis mechanisms
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Metabolic dysregulation as the underlying principle of integrated pathophysiology of obesity-associated chronic diseases: Molecular Landscape of Complex Lifestyle Modification
    Program:
    Duration: 1. 8. 2024 – 30. 6. 2026
  • Effects of regular exercise training on molecular, cellular and whole body processes associated with ageing: : Multi-organ integrative approach
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
Finished
  • Identification and validation of biomarkers and underlying molecular pathways of late toxicity of curative treatment in testicular germ cell tumors
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Exercise in prevention & treatment of chemotherapy-related late toxicity in testicular germ cell cancer survivors: the role of skeletal muscle
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2023
  • Strengthening of research, development and innovation capacities of translational biomedical research of human diseases
    Program:
    Duration: 1. 1. 2020 – 30. 6. 2023
  • Mechanisms of skeletal muscle adaptation to regular exercise in patients with chronic metabolic and inflammatory disease
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Molecular mediators of physical exercise and carnosine induced effects in patients with preclinical and early stage neurodegenerative disease
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Multiple sclerosis - The role of mitochondrial dysfunction in insulin resistance.
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Identification of biomarkers associated with late toxicity of chemotherapy in testicular germ cell tumors
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2020
  • Molecular mechanisms of thermogenesis in brown fat in humans in relationship to obesity, physical activity and hardening
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • The role of Carnosine and Vitamine D in the Prevention of Type 2 Diabetes: molecular mechanisms of action
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • Transfer of genetic knowledge of endocrine research into clinical praxis
    Program: EU Structural Funds Research & Development
    Duration: 1. 11. 2010 – 31. 8. 2013
  • Tissue inflammation, metabolic and endocrine character of subcutaneous and visceral adipose tissue and oxidative capacity of skeletal muscle in pathophysiology of insulin resistance in individuals with extreme obesity
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 1. 2013
  • Molecular-genetic mechanism of sympathetic regulation of adipose tissue in mammals under stress exposure.
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2012
  • Morphological-functional aspects of the adipose tissue in patients with chronic obstructive pulmonary disease (COPD)
    Program: VEGA
    Duration: 1. 1. 2010 – 31. 12. 2012
  • Relationship between systemic inflammation, insulin resistance and cardiovascular risk in patients with obstructive sleep apnea
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Bioactive food components, mitochondrial function and health
    Program:
    Duration: 1. 5. 2007 – 31. 5. 2011
  • Adipose tissue and innate inflammation in obese subjects and subjects with growth hormone deficiency
    Program: VEGA
    Duration: 1. 1. 2007 – 1. 12. 2009
  • The role mitochondria and cytokines from the skeletal muscle and adipose tissue during the development of diet-induced obesity
    Program: VEGA
    Duration: 1. 1. 2007 – 1. 12. 2009
  • Effect of alpha2 adrenergic receptors on functional plasticity of hypothalamic oxytocinergic neurons in vasopressin deficient, hypernatremic and hyperosmotic Brattleboro rats
    Program: VEGA
    Duration: 1. 1. 2007 – 1. 12. 2009
Employees