Projects

doc. Ing. Čestmír Altaner, DrSc.
senior scientist

International

Finished
  • Influence of stem cells on life span of mice
    Program: Bilateral - other
    Duration: 1. 1. 2003 – 31. 12. 2009

National

Current
  • Reprogramming pancreatic ductal adenocarcinoma microenvironment towards immunotherapy
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • Analysis of the clinical relevance of EDA2R gene duplication in autistic boy stem cells to his disease.Characterization of EDA2R receptor expression in stem cells obtained from the dental pulp of permanent and temporary teeth.
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2025
Finished
  • Suicide gene therapy mediated by mesenchymal stromal and pancreatic tumor cell-excreted extracellular vesicles in the treatment of pancreatic ductal adenocarcinoma
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2025
  • TArgetiNg Dna mEthylation by epigenetic editing and its implementation into personalised diagnostics and therapy of uveal Melanoma
    Program: SRDA
    Duration: 1. 8. 2018 – 31. 12. 2022
  • Study of Exosome Nanoparticle Properties Secreted by Mesenchymal Stromal Cells Transduced by the HerpesSimplex Virus Thymidine Kinase (TK/HSV) Suicide Gene to Be Used for Innovative Glioblastoma Therapy
    Program: VEGA
    Duration: 1. 1. 2020 – 1. 12. 2022
  • Human mesenchymal stem cells and their use in regenerative therapy and gene therapy for cancer
    Program: Other projects
    Duration: 1. 1. 2006 – 31. 12. 2015
  • Nanoparticles in cancer gene therapy and labeling of human stem cells with magnetic fluid and their follow up by MRI
    Program: Other projects
    Duration: 1. 1. 2008 – 31. 12. 2012
  • Gene-cell therapy of cancer using a self-inactivating - retroviral vectors inducibly expressing tumour necrosis factor alpha in human mesenchymal stem cells
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Human mesenchymal stem cells as cytoreagents for metastasis-targeted therapy
    Program: SRDA
    Duration: 1. 6. 2008 – 30. 6. 2011
  • Biological effect of novel RET gene mutation connected to multiple endocrine neoplasia type 2
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Interaction of human adipose-tissue derived mesenchymal stem cells with human cancer cells
    Program: VEGA
    Duration: 1. 1. 2007 – 31. 12. 2009
  • Gene therapy for cancer with retrovirus vectors. Testing of vectors with tumor necrosis factor and vectors with siRNA expression cassette
    Program: VEGA
    Duration: 1. 1. 2006 – 31. 12. 2008