Projects

Mgr. Miroslav Chovanec, PhD.
Director

International

Finished
  • A Coordination and Support Action to prepare UNCAN.eu platform
    Program: Horizon Europe
    Duration: 1. 9. 2022 – 30. 11. 2023

National

Current
  • Regulation of iron transport as a factor contributing to the chemoresistance of testicular tumours
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Role of DNA damage and repair in response of urogenital cancers to cisplatin-based chemotherapy
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
Finished
  • Is hypoxia a master modulator of DNA repair capacity and mitochondrial dynamics in chemotherapy response in urogenital malignancies?
    Program: VEGA
    Duration: 1. 1. 2021 – 31. 12. 2024
  • Study of biological effects of H2S/NO/selenium products and molecular mechanisms of their actions
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Is HIF-1a a master regulator of DNA repiar capacity and chemotherapy response in testicular germ cell tumors?
    Program: SRDA
    Duration: 1. 7. 2020 – 31. 12. 2023
  • Integrative strategy in the development of personalized medicine of selected malignant cancer diseases and its effect on the quality of life
    Program:
    Duration: 1. 9. 2019 – 30. 6. 2023
  • Identification of biomarkers of resistance to cisplatin-based chemotherapy in urogenital cancer
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Molecular biomarkers of relapse in seminoma clinical stage I patients
    Program: Other projects
    Duration: 1. 10. 2019 – 21. 12. 2022
  • Turning cisplatin-resistant testiular germ cell tumors into a curable disease
    Program: SRDA
    Duration: 1. 8. 2018 – 31. 12. 2021
  • Is DNA repair beyond good curability in testicular germ cell tumours?
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2020
  • Study of repair of chemotherapy-induced DNA damage using Saccharomyces cerevisiae as a model suystem
    Program: SRDA
    Duration: 1. 7. 2015 – 30. 6. 2018
  • Regulation of the ligation step of non-homologous end-joining
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2017
  • Identification of biomarkers associated with treatment resistance in testicular germ cell tumors
    Program: SRDA
    Duration: 1. 7. 2012 – 31. 12. 2015
  • Regulation of DNA double-strand repair mechanism choice
    Program: SRDA
    Duration: 1. 5. 2011 – 30. 10. 2014
  • Centre of Excellence for Translational Research in Molecular medicine
    Program: EU Structural Funds Research & Development
    Duration: 1. 6. 2010 – 31. 5. 2012
  • Molecular mechanisms of DNA interstrand cross-link repair in Saccharomyces cerevisiae
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Center of Excelence for Translational Research in Molecular Medicine
    Program: EU Structural Funds Research & Development
    Duration: 1. 6. 2009 – 31. 5. 2011
  • Assessment of spontaneous mutagenesis in yeast cells expressing the human DNA ligase proteins found in LIG4 patients
    Program: SRDA
    Duration: 2. 2. 2009 – 31. 12. 2010
  • Further in vivo characterization of the mutant and polymorphic DNA ligase IV proteins found in LIG4 patients
    Program: SRDA
    Duration: 2. 5. 2006 – 30. 4. 2009
  • Contribution of homologous recombination and non-homologous end-joining to DNA double-strand break repair after oxidative stress in the budding yeast Saccharomyces cerevisiae
    Program: VEGA
    Duration: 1. 1. 2006 – 31. 12. 2008