Projects

Ing. Ľuboš Čipák, PhD.

National

Current
  • Functional analysis of uncharacterized spliceosome-associated factors of Schizosaccharomyces pombe
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Analysis of the role of G-patch proteins in regulating RNA helicases involved in pre-mRNA splicing in Schizosaccharomyces pombe
    Program: SRDA
    Duration: 1. 9. 2024 – 30. 6. 2027
  • Characterization of novel proteins involved in the regulation of pre-mRNA splicing
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Analysis of the role of newly identified spliceosome-associated factors in the assembly and remodeling of early splicing complexes and the activation of the spliceosome in the fission yeast Schizosaccharomyces pombe
    Program:
    Duration: 1. 8. 2024 – 30. 6. 2026
  • The role of DNA repair proteins in gene repression
    Program: SRDA
    Duration: 1. 7. 2022 – 30. 6. 2026
  • Detailed analysis and elucidation of functions of Cka1 and Ksg1 protein kinases using the conditional ATP analog-sensitive mutants
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
Finished
  • Post-translational regulation of pre-mRNA splicing factors
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2024
  • Functional analysis of regulation of DEAH/RHA helicases
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Dbl2 protein as a novel regulator of genome stability and dynamics in fission yeast
    Program: SRDA
    Duration: 1. 7. 2019 – 31. 12. 2022
  • Regulation of the Swi5-Sfr1 complex by protein phosphorylation
    Program: SRDA
    Duration: 1. 8. 2018 – 31. 10. 2022
  • Role of protein kinases in processes involved in maintenance of genome stability
    Program: VEGA
    Duration: 1. 1. 2018 – 31. 12. 2021
  • Unravelling the mechanisms of post-translational regulation of RNA splicing factors in maintenance of genome integrity
    Program: SRDA
    Duration: 1. 7. 2017 – 30. 6. 2021
  • Detailed characterization and further improvement of system for induction of synchronous meiosis at optimal temperature
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2019
  • Identification of substrates of essential protein kinases using shokat mutants
    Program: SASPRO
    Duration: 1. 4. 2015 – 31. 12. 2018
  • Role of protein kinases in regulation of chromosome segregation
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2017
  • Role of essential protein kinases in regulation of meiotic chromosome segregation
    Program: SRDA
    Duration: 1. 10. 2013 – 30. 9. 2016
  • PARP-1 inhibitors - genetically specific drugs for BRCA1/2 associated breast cancers
    Program: VEGA
    Duration: 1. 1. 2010 – 31. 12. 2012
  • Centre for Signalosome Research
    Program: SRDA
    Duration: 1. 7. 2008 – 30. 6. 2011
  • Effect of natural compounds isothiocyanates (ITCs) on cellular mechanisms and markers associated with aggressive phenotype and treatment responsiveness in breast and ovarian cancer
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • DNA protective agents available in cancer research
    Program: VEGA
    Duration: 1. 1. 2007 – 31. 12. 2009