Projects

Mgr. Alžbeta Bujňáková Mlynarčíková, PhD.

National

Current
  • Assessment of protective action of selected phytochemicals against metal nanoparticle-induced neurotoxicity using in vitro cell models
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Biologically relevant mixtures of endocrine disruptors: effects on in vitro models of ovarian intrafollicular processes and ovarian cancer cell lines
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Investigation of new molecular regulatory mechanisms of selected biologically active 4H-pyran-4-ones in relation to their prospective applicability in human oncology
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2026
Finished
  • Molecular mechanisms of trialkyl-/triaryltin isothiocyanates\' and carboxylates\' antitumour properties - novel ligands of nuclear retinoid X receptors in rat mammary gland carcinomas and human tumour cell lines
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2025
  • Potential risk of use of analogs of endocrine disruptor Bisphenol A: determination of cellular and molecular effects in a spectrum of in vitro gonadal cell cultures
    Program: SRDA
    Duration: 1. 7. 2019 – 30. 6. 2023
  • Impact of selected metal nanoparticles on steroidogenesis: comparison of in vitro cell models
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2022
  • The safety of use of analogs of the endocrine disruptor Bisphenol A: evaluation of effects on in vitro models of ovarian intrafollicular processes and and ovarian cancer cell lines
    Program: VEGA
    Duration: 1. 1. 2018 – 31. 12. 2020
  • Novel synergistic antitumour properties ofnuclear retinoid X receptor (RXR) agonists as a consequence of the conditional RXR-RAR heterodimer formation in human breast cancer cells
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Potential risk of metal and metal oxide nanoparticles used for biomedical applications: focus on reproductive and immune systems and brain
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Investigation of anatomical-functional differences between the effects of aripiprazole and quetiapine, atypical antipsychotics with simiral terapeutic indications, but different impact on brain dopaminergic receptors, in experimental animals
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Characterization of effects of neonatal exposure to nanoparticles in selected brain structures and reproductiveorgans in adult and infantile female rats
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • Study of selected endocrine disruptors with phytochemicals on in vitro models of ovarian intrafollicular processess and hormone-sensitive cancer cell lines
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2017
  • Acute and reproductive toxicity of selected types of nanoparticles: an in vivtro model
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • Estrogenic activities of phtalate/phenol derivatives on cell poliferation
    Program: VEGA
    Duration: 1. 1. 2007 – 1. 12. 2009
  • Effect of binary mixtures of xenoestrogens on ovarian intrafollicula processes
    Program: VEGA
    Duration: 1. 1. 2006 – 1. 12. 2007