Projects

RNDr. Nataša Hlaváčová, PhD.

International

Current
  • Reward-stress interactions as neurobiological substrate for resilience and vulnerability in mental health and depression: A translational large-scale project
    Program: ERANET
    Duration: 1. 1. 2024 – 31. 12. 2026
  • Genome Editing to Treat Humans Diseases
    Program: COST
    Duration: 15. 9. 2022 – 14. 9. 2026
Finished
  • The importance of brain-gut interaction in the development of posttraumatic stress disorder based upon preclinical studies
    Program: Mobility
    Duration: 1. 1. 2023 – 31. 12. 2024
  • UNveiling the MEchanism(s) underlying the switch to mania during antidepressant treatment: The role of glutamate
    Program: ERANET
    Duration: 1. 7. 2019 – 31. 1. 2024
  • Effects of vortioxetine in the tryptophan-depletion model of SSRI-resistant depression in female rats
    Program: Other
    Duration: 1. 7. 2014 – 31. 12. 2018
  • Vesicular glutamate transporter 3 knockout mice and changes in gene expression of the transporter: relation to stress hormones, behavior and animal models of mood disorders
    Program: Inter-academic agreement
    Duration: 1. 1. 2016 – 31. 12. 2018
  • Developing a rat model of depression based on tryptophan deficiency
    Program: Bilateral - other
    Duration: 1. 5. 2011 – 31. 12. 2017
  • Aldosterone and Mineralocorticoid Receptor
    Program: COST
    Duration: 23. 11. 2016 – 30. 11. 2017

National

Current
  • CARDIOvascular protection mediated by alfa1AMPK against metabolic syndrome-mediated ENdothelial Dysfunction – identifying new risk factors
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • Coping with psychosocial stress situations in patients with depressive disorder in relation to age and unravelling the mechanisms involved
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Searching for new neurobiological targets implicated in stress-related mental disorders in unique animal models
    Program:
    Duration: 1. 8. 2024 – 30. 6. 2026
  • Enhancement of endocannabinoid signaling as a promising target for the treatment of stress-related psychiatric disorders
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
Finished
  • Activation of the VGF/BDNF/TrkB pathway by synthetic mRNA encapsulated in polyplex nanoparticles: effects on neural excitability, neuroplasticity and animal behavior
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2025
  • Bridge between the mental state and neuroendocrine function of mother and her child: the mechanisms involved
    Program: SRDA
    Duration: 1. 7. 2019 – 30. 6. 2023
  • Interrelationships between endocrine and mental characteristics of women in reproductive age
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Identification of psychological and somatic markers in relation to vulnerability to stress and analysis of the effectiveness of psychological interventions
    Program: SRDA
    Duration: 1. 8. 2018 – 31. 7. 2022
  • Mineralocorticoid receptors in novel target tissues – pathophysiological relevance and underlying mechanisms
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2021
  • Molecular bases of depressive disorders in children and adolescents, effect of omega-3 fatty acids and oxidative stress
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 12. 2020
  • Prenatal and postnatal effects of delta and mu opioid receptor ligands on the hippocampal development and function.
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 10. 2020
  • Interaction of nitrergic, neurotrophic and endocrine signaling in the etiopathogenesis of schizophrenia
    Program: SRDA
    Duration: 1. 7. 2015 – 30. 6. 2019
  • The clinical significance of the relationship between aldosterone and depression and the regulatory mechanisms involved
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
  • Cognitive, personal and psychophysiological factors of the stress in the context of the relationship between anxiety and allergies and their optimalisation
    Program: SRDA
    Duration: 1. 10. 2013 – 30. 9. 2017
  • Mechanisms of atypical effects of hormones
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • Neuroendocrine mechanisms related to mental state and to the action of psychotropic drugs
    Program: VEGA
    Duration: 1. 1. 2005 – 1. 12. 2007