Projects

RNDr. Nadežda Lukáčová, DrSc.
Deputy director, Head of the Laboratory of neurochemistry and neurophysiology

International

Finished
  • The potential protective role of siponimod in neurodegeneration/spinal cord injury.
    Program: Mobility
    Duration: 1. 1. 2023 – 31. 12. 2024
  • Endurance Training and/or administration of neurotrophic factor as a novel therapeutic approach for treatment of Spinal Cord Injury
    Program: Inter-academic agreement
    Duration: 1. 1. 2016 – 31. 12. 2018
  • The response of nitric oxide synthase and calcium-binding proteins in brain stem after spinal cord injury
    Program: Inter-academic agreement
    Duration: 1. 1. 2010 – 31. 12. 2012
  • The effect of endurance training on NOS and parvalbumin activity in proprioceptive afferentation if the spinal cord
    Program: Inter-academic agreement
    Duration: 1. 1. 2007 – 31. 12. 2009
  • Neuroprotective vs neurodegenerative role of nitric oxide in CNS under neuropathological disorders
    Program: Inter-academic agreement
    Duration: 1. 1. 2004 – 31. 12. 2006

National

Current
  • Regulatory mechanisms of mutual communication between hypoxia-ischemia and inflammation during the acute and subacute phase of traumatic spinal cord injury and Siponimod treatment
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2027
  • Neuroprotective and regenerative potential of post-traumatic cure targeted to Angiotensin II receptors
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • The effect of NG2 positive cell population on extent of damage and functional recovery following spinalal cord injury
    Program: VEGA
    Duration: 1. 1. 2024 – 31. 12. 2026
  • The effect of the AT2 receptor stimulation on revascularization of severe injured spinal cord
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2025
Finished
  • The development of translationally relevant regenerative and reparative strategies after spinal cord trauma
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Regulation of M1/M2 polarization: the effect on neuron survival, axonal growth and functional recovery after spinal cord trauma
    Program: VEGA
    Duration: 1. 1. 2021 – 31. 12. 2023
  • Effect of electrical stimulation on regeneration of injured neural pathways.
    Program: VEGA
    Duration: 1. 1. 2020 – 31. 12. 2023
  • The neuroprotection of synergic effect of the AT1 receptor blockade and AT2 receptor stimulation after traumatic spinal cord injury
    Program: SRDA
    Duration: 1. 7. 2019 – 30. 6. 2023
  • Open scientific community for modern interdisciplinary research in medicine
    Program:
    Duration: 1. 11. 2019 – 30. 6. 2023
  • Regulation of Angiotensin II receptors in neuroprotection after traumatic spinal cord injury
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2021
  • The application of combined therapy to suppress secondary damage after spinal cord trauma
    Program: SRDA
    Duration: 1. 7. 2016 – 31. 10. 2020
  • The effect of GDNF vector and block of inhibition molecules on interneuronal connections and axonal outgrowth after cervical and thoracic spinal cord injury
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2019
  • Neuroprotective mechanisms of the AT2 receptor stimulation after traumatic spinal cord injury.
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2018
  • Endogenous stimulation and exogenous application of neurotrophic factors to reduce secondary damage in model of spinal cord compression
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2016
  • -
    Program: EU Structural Funds Research & Development
    Duration: 10. 7. 2013 – 30. 6. 2016
  • A suppression of secondary injury of trauma-injured spinal cord using local hypothermia combined with local perfusion of neuroprotective substances
    Program: VEGA
    Duration: 1. 1. 2013 – 31. 12. 2015
  • Centre of Excellence for Research on the regulatory role of nitric oxide in diseases of civilization
    Program:
    Duration: 4. 8. 2011 – 30. 6. 2015
  • Formation and development of a diagnostic procedure in the treatment of trauma - injured spinal cord
    Program: EU Structural Funds Research & Development
    Duration: 1. 11. 2010 – 30. 4. 2015
  • Molecular mechanisms of neuroprotection and ischemic tolerance
    Program: VEGA
    Duration: 1. 1. 2012 – 31. 12. 2014
  • NO/ANP-mediated cGMP synthesis in neuron-glial interaction after spinal cord injury and Baclofen treatment
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 12. 2013
  • Modulation somato-sensory neural pathways by Angiotensin II. Effect of Angiotensin II receptor blockade on nociceptive signaling.
    Program: VEGA
    Duration: 1. 1. 2010 – 31. 12. 2012
  • Science in Slovakia - if we do not know something, we do not feel need for it.
    Program: SRDA
    Duration: 3. 9. 2009 – 31. 8. 2012
  • Molecular neurobiological and pharmacological corelations of neuroprotection and ischemic tolerance
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Centre of excellence for cardiovascular research
    Program:
    Duration: 1. 1. 2007 – 31. 12. 2010
  • The disturbance of NO/cGMP signaling pathway in cervical spinal cord injury
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Causal genesis of spasticity and therapeutic possibilities.
    Program: SRDA
    Duration: 7. 2. 2007 – 30. 6. 2010
  • Molecular analysis of ischemia-reperfusion changes in CNS and neuroprotective mechanisms.
    Program: VEGA
    Duration: 1. 1. 2006 – 31. 12. 2008
  • Distribution of spinal and supraspinal neuronal pools expressing nNOS and NK-1 receptor involved in chronic pain development
    Program: VEGA
    Duration: 1. 1. 2005 – 31. 12. 2007
  • The participation of nitric oxide synthase on nociceptive and proprioceptive afferentation
    Program: VEGA
    Duration: 1. 1. 2005 – 31. 12. 2007
  • Postraumatic regenerability of short propriospinal and long premotor truncospinal conductive systems in the spinal cord.
    Program: SRDA
    Duration: 1. 8. 2002 – 31. 12. 2005
Employees