Nervous System Development

Research Topic

We live in a world where mental health is under significant pressure. Due to social, environmental, and nutritional influences, significant changes occur in the structures and functions of both the central and peripheral nervous systems. The prevalence of neuropsychiatric diseases and various behavioural disorders requires a thorough understanding of their pathogenesis and and qualified therapeutic approaches based on scientific evidence. Our goal is to understand the mechanisms of nervous system development, neuronal cell formation and differentiation, as well as to comprehend the dynamics of neuroendocrine responses to various stimuli. We aim to elucidate neuroendocrine stress reactions during tumorigenesis, clarify the mechanisms of pharmacotherapy in psychopathological conditions, and contribute to the understanding of autism etiology. The research involves the use of animal models, primary neuronal cell cultures, as well as human neuronal cell lines and nervous tissue. Methodologically, the laboratory covers gene expression analysis, protein quantification, immunohistochemical and immunocytochemical techniques, and a broad spectrum of behavioral tests.

Our research activities primarily focus on:

1. brain development and neuronal cell differentiation
2. psychiatric, cardiovascular and metabolic comorbidities of brain diseases
3. stress and its consequences
4. behavioural changes during development and after chronic stress conditions

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Head of the Research Group

Employees

Title	Name	E-mail	Phone	ORCID
Mgr., PhD.	Bačová Zuzana		02/ 32295 kl. 231, 229, 239, 240
doc. RNDr., PhD.	Bakoš Ján		02/ 32295 kl. 232, 229, 239, 240
Mgr., PhD.	Benický Július
Mgr., PhD.	Blaško Filip
Ing.	Bodorová Barbora
Mgr.	Dziewiczová Lila
Mgr., PhD.	Havránek Tomáš		02/ 32295 kl. 233
Mgr., PhD.	Horváthová Ľubica		02/ 32295 kl. 223, 211, 213
RNDr., DrSc.	Kiss Alexander		02/ 32295 kl. 225, 211, 213
Ing., PhD.	Lauková Marcela
Mgr., PhD.	Mihalj Denisa		02/ 32295 kl. 230
prof. MUDr., DrSc.	Mravec Boris		02/ 32295 kl. 226
RNDr., PhD.	Osacká Jana		02/ 32295 kl. 214, 223, 211, 213
MUDr., PhD.	Paliokha Ruslan
doc. PharmDr., PhD.	Pirník Zdenko		02/ 32295 kl. 223, 211
Ing., PhD.	Reichová Alexandra		02/ 32295 kl. 230
Mgr., PhD.	Ševčíková Tomášková Zuzana
Ing., PhD.	Tillinger Andrej		02/ 32295 kl. 227, 212, 213
Ing., PhD.	Vargovič Peter		02/ 32295 kl. 279, 281