Publications

2022

Nemethova, V., Mazancova, P., Selc, M., Jakic, K., Uhelska, L., Nemethova, B., Poturnayova, A., Drgona, L., Babelova, A., Razga, F. (2022). Effective Reduction of SARS-CoV-2 RNA Levels Using a Tailor-Made Oligonucleotide-Based RNA Inhibitor. Viruses, 14(4), 685. doi: 10.3390/v14040685.

Tulinska, J., Krivosikova, Z., Liskova, A., Mikusova, M. L., Masanova, V., Rollerova, E., Stefikova, K., Wsolova, L., Babelova, A., Tothova, L., Busova, M., Babickova, J., Uhnakova, I., Alacova, R., Dusinska, M., Horvathova, M., Szabova, M., Vecera, Z., Mikuska, P., Coufalik, P., Krumal, K., Alexa, L., Piler, P., Thon, V., Docekal, B. (2022). Six-week inhalation of lead oxide nanoparticles in mice affects antioxidant defense, immune response, kidneys, intestine and bones. Environmental Science: Nano, 9(2), 751-766. doi: 10.1039/d1en00957e.

Bertokova, A., Svecova, N., Kozics, K., Gabelova, A., Vikartovska, A., Jane, E., Hires, M., Bertok, T., Tkac, J. (2022). Exosomes from prostate cancer cell lines: Isolation optimisation and characterisation. Biomedicine & Pharmacotherapy, 151. doi: 10.1016/j.biopha.2022.113093.

Bálintová, L., Matúšková, M., Gábelová, A. (2022). The evaluation of the efficacy and potential genotoxic hazard of combined SAHA and 5-FU treatment in the chemoresistant colorectal cancer cell lines. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 874. doi: 10.1016/j.mrgentox.2022.503445

Soltysova, A., Begerova, P., Jakic, K., Kozics, K., Sramkova, M., Meese, E., Smolkova B., Gabelova, A. (2022). Genome-wide DNA methylome and transcriptome changes induced by inorganic nanoparticles in human kidney cells after chronic exposure. Cell Biology and Toxicology, 1-18. doi: 10.1007/s10565-021-09680-3.

Buocikova, V., Longhin, E. M., Pilalis, E., Mastrokalou, C., Miklikova, S., Cihova, M., Poturnayova, A., Mackova, K., Babelova., A., Trnkova., L., El Yamani, N., Zheng, C. Y., Rios-Mondragon, I., Labudova, M., Csaderova, L.,Kuracinova, K. M., Makovicky, P., Kucerova, L., Matuskova, M., Cimpan, M. R., Dusinska, M., Babal, P., Chatziioannou, A., Gabelova, A., Runden-Pran, E., Smolkova, B. (2022). Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models. Biomedicine & Pharmacotherapy, 147. doi: 10.1016/j.biopha.2022.112662.

Dubaj, T., Kozics, K., Sramkova, M., Manova, A., Bastús, N. G., Moriones, O. H., Kohl, Y., Dusinska, M., Runden-Pran, E., Puntes, V., Nelson, A., Gabelova, A., Simon, P. (2022). Pharmacokinetics of PEGylated Gold Nanoparticles: In Vitro—In Vivo Correlation. Nanomaterials, 12(3), 511. doi: 10.3390/nano12030511.

Blažíčková, M., Blaško, J., Kubinec, R., Kozics, K. (2022). Newly Synthesized Thymol Derivative and Its Effect on Colorectal Cancer Cells. Molecules, 27(9), 2622. doi: 10.3390/molecules27092622.

2021

Kohl, Y., Biehl, M., Spring, S., Hesler, M., Ogourtsov, V., Todorovic, M., Owen, J., Elje, E., Kopecka, K., Moriones, O. H., Bastus, N. G., Simon, P., Dubaj, T., Runden-Pran, E., Puntes, V., William, N., von Briesen, H., Wagner, S., Kapur, N., Mariussen, E., Nelson, A., Gabelova, A., Dusinska, M., Velten, T., Knoll, T. (2021). Microfluidic in vitro platform for (nano) safety and (nano) drug efficiency screening. Small, 17(15). doi: 10.1002/smll.202006012.

Kozics, K., Sramkova, M., Kopecka, K., Begerova, P., Manova, A., Krivosikova, Z., Sevcikova, Z., Liskova, A., Rollerova, E., Dubaj, T., Puntes, V., Wsolova, L., Simon, P., Tulinska, J., Gabelova, A. (2021). Pharmacokinetics, biodistribution, and biosafety of PEGylated gold nanoparticles in vivo. Nanomaterials, 11(7). doi: 10.3390/nano11071702.

Svitkova, B., Zavisova, V., Nemethova, V., Koneracka, M., Kretova, M., Razga, F., Ursinyova, M., Gabelova, A. (2021). Differences in surface chemistry of iron oxide nanoparticles result in different routes of internalization. Beilstein journal of nanotechnology, 12(1), 270-281. doi: 10.3762/bjnano.12.22.

Altanerova, U., Jakubechova, J., Benejova, K., Priscakova, P., Repiska, V., Babelova, A., Smolkova, B., Altaner, C. (2021). Intracellular prodrug gene therapy for cancer mediated by tumor cell suicide gene exosomes. International journal of cancer, 148(1), 128-139. doi: 10.1002/ijc.33188.

Kalavska, K., Sestakova, Z., Mlcakova, A., Kozics, K., Gronesova, P., Hurbanova, L., Miskovska, V., Rejlekova, K., Svetlovska, D., Sycova-Mila, Z., Obertova, J., Palacka, P., Mardiak, J., Chovanec, M., Chovanec, M., Mego, M. (2021). Are Changes in the Percentage of Specific Leukocyte Subpopulations Associated with Endogenous DNA Damage Levels in Testicular Cancer Patients?. International Journal of Molecular Sciences, 22(15), 8281. doi: 10.3390/ijms22158281.

Opálková Šišková, A., Mosnáčková, K., Hrůza, J., Frajová, J., Opálek, A., Bučková, M., Kozics, K., Peer, P., Eckstein Andicsová, A. (2021). Electrospun poly (ethylene terephthalate)/silk fibroin composite for filtration application. Polymers, 13(15), 2499. doi: 10.3390/polym13152499.

Kapustová, M., Puškárová, A., Bučková, M., Granata, G., Napoli, E., Annušová, A., Mesarosova, M., Kozics, K., Pangallo, D., Geraci, C. (2021). Biofilm inhibition by biocompatible poly (ε-caprolactone) nanocapsules loaded with essential oils and their cyto/genotoxicity to human keratinocyte cell line. International Journal of Pharmaceutics, 606, 120846. doi: 10.1016/j.ijpharm.2021.120846.

Hricovíniová, J., Hricovíniová, Z., Kozics, K. (2021). Antioxidant, Cytotoxic, Genotoxic, and DNA-Protective Potential of 2, 3-Substituted Quinazolinones: Structure—Activity Relationship Study. International Journal of Molecular Sciences, 22(2), 610. doi: 10.3390/ijms22020610.

Tyciakova, S., Valova, V., Svitkova, B., & Matuskova, M. (2021). Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells. BMC cancer, 21(1), 1-13. doi: 10.1186/s12885-021-08237-1.

2020

Buocikova, V., Rios-Mondragon, I., Pilalis, E., Chatziioannou, A., Miklikova, S., Mego, M., Pajuste, K., Rucins, M., El Yamani, N., Longhin, E. M., Sobolev, A., Freixanet, M., Puntes, V., Plotniece, A., Dusinska, M., Cimpan, M. R., Gabelova, A., Smolkova, B. (2020). Epigenetics in breast cancer therapy—New strategies and future nanomedicine perspectives. Cancers, 12(12), 3622. doi: 10.3390/cancers12123622.

Gabelova, A. (2020). 7H-Dibenzo [c, g] carbazole: Metabolic pathways and toxicity. Chemico-Biological Interactions, 323, doi: 10.1016/j.cbi.2020.109077.

Møller, P., Azqueta, A., Boutet-Robinet, E., Koppen, G., Bonassi, S., Milić, M., Gajski, G., Costa, S., Teixeira, J. P., Pereira, C.C., Dusinska, M., Godschalk, R., Brunborg, G., Gutzkow, K.B., Giovannelli, L., Cooke, M.S., Richling, E., Laffon, B., Valdiglesias, V., Basaran, N., Del Bo’, C., Zegura, B., Novak, M., Stopper, H., Vodicka, P., Vodenkova, S., de Andrade, V. M., Sramkova, M., Gabelova, A., Collins, A., Langie, S. A. (2020). Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results. Nature Protocols, 15(12), 3817-3826. doi: 10.1038/s41596-020-0398-1.

Selc, M., Razga, F., Nemethova, V., Mazancova, P., Ursinyova, M., Novotova, M., Kopecka K., Gabelova A., Babelova, A. (2020). Surface coating determines the inflammatory potential of magnetite nanoparticles in murine renal podocytes and mesangial cells. RSC advances, 10(40), 23916-23929. doi: 10.1039/d0ra03133j.

Tulinska, J., Masanova, V., Liskova, A., Mikusova, M. L., Rollerova, E., Krivosikova, Z., Stefikova, K., Uhnakova, I., Ursinyova, M., Babickova, J., Babelova, A., Busova, M., Tothova, L., Wsolova, L., Dusinska, M., Sojka, M., Horvathova, M., Alacova, R., Vecera, Z., Mikuska, P., Coufalik, P., Krumal, K., Capka, L., Docekal, B. (2020). Six-week inhalation of CdO nanoparticles in mice: The effects on immune response, oxidative stress, antioxidative defense, fibrotic response, and bones. Food and Chemical Toxicology, 136, 110954. doi: 10.1016/j.fct.2019.110954.

Kosik, P., Durdik, M., Jakl, L., Skorvaga, M., Markova, E., Vesela, G., Vesela, G., Vokalova, L., Kolarikova, L., Horvathova, E., Kozics, K., Belyaev, I. (2020). DNA damage response and preleukemic fusion genes induced by ionizing radiation in umbilical cord blood hematopoietic stem cells. Scientific reports, 10(1), 1-12. doi: 10.1038/s41598-020-70657-z.

2019

Gabelova, A., Kozics, K., Kapka-Skrzypczak, L., Kruszewski, M., Sramkova, M. (2019). Nephrotoxicity: topical issue. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 845, 402988. doi: 10.1016/j.mrgentox.2018.11.012.

Kapka-Skrzypczak, L., Czajka, M., Sawicki, K., Matysiak-Kucharek, M., Gabelova, A., Sramkova, M., Bartyzel-Lechforowicz, H., Kruszewski, M. (2019). Assessment of DNA damage in Polish children environmentally exposed to pesticides. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 843, 52-56. doi: 10.1016/j.mrgentox.2018.12.012.

Kruszewski, M., Sikorska, K., Meczynska-Wielgosz, S., Grzelak, A., Sramkova, M., Gabelova, A., & Kapka-Skrzypczak, L. (2019). Comet assay in neural cells as a tool to monitor DNA damage induced by chemical or physical factors relevant to environmental and occupational exposure. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 845, 402990. doi: 10.1016/j.mrgentox.2018.11.014.

Sramkova, M., Kozics, K., Masanova, V., Uhnakova, I., Razga, F., Nemethova, V., Mazancova, P., Kapka-Skrzypczak, L., Kruszewski, M., Novotova, M., Puntes, V. F., Gabelova, A. (2019). Kidney nanotoxicity studied in human renal proximal tubule epithelial cell line TH1. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 845, 403017. Doi: 10.1016/j.mrgentox.2019.01.012.

Zavisova, V., Koneracka, M., Gabelova, A., Svitkova, B., Ursinyova, M., Kubovcikova, M., Antal, I., Khmara, I., Jurikova, A., Molcan, M., Ognjanovic, M., Antic, B., Kopcansky, P. (2019). Effect of magnetic nanoparticles coating on cell proliferation and uptake. Journal of Magnetism and Magnetic Materials, 472, 66-73. doi: 10.1016/j.jmmm.2018.09.116.

Gajski, G., Žegura, B., Ladeira, C., Pourrut, B., Del Bo, C., Novak, M., Sramkova, M., Milic, M., Gutzkow, K. B., Costa, S., Dusinska, M., Brunborg, G., Collins, A. (2019). The comet assay in animal models: From bugs to whales–(Part 1 Invertebrates). Mutation Research/Reviews in Mutation Research, 779, 82-113. doi: 10.1016/j.mrrev.2019.02.003.

Kozics, K., Bučková, M., Puškárová, A., Kalászová, V., Cabicarová, T., Pangallo, D. (2019). The effect of ten essential oils on several cutaneous drug-resistant microorganisms and their cyto/genotoxic and antioxidant properties. Molecules, 24(24), 4570. doi: 10.3390/molecules24244570.

Durdik, M., Kosik, P., Markova, E., Somsedikova, A., Gajdosechova, B., Nikitina, E., Horvathova, E., Kozics, K., Davis, D., Belyaev, I. (2019). Microwaves from mobile phone induce reactive oxygen species but not DNA damage, preleukemic fusion genes and apoptosis in hematopoietic stem/progenitor cells. Scientific reports, 9(1), 1-12. Doi: 10.1038/s41598-019-52389-x.

Opattova, A., Horak, J., Vodenkova, S., Kostovcikova, K., Cumova, A., Macinga, P., Galanova, N., Rejhova, A., Vodickova, L., Kozics, K., Turnovcova, K., Hucl, T., Sliva, D., Vodicka, P. (2019). Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 845, 403065. doi: 10.1016/j.mrgentox.2019.06.001.

SMOLKOVÁ, B., DUŠINSKÁ, M., GÁBELOVÁ, A. Epigenetic effects of nanomaterials. In Encyclopedia of Environmental Health : 2nd edition. – Elsevier, 2019, p. 678-685. ISBN 978-0-44-463951-6. Typ: AECA.

2018

Zarska M, Sramek M, Novotny F, Havel F, Babelova A, Mrazkova B, Benada O, Reinis M, Stepanek I, Musilek K, Bartek J, Ursinyova M, Novak O, Dzijak R, Kuca K, Proska J, Hodny Z. Biological safety and tissue distribution of (16-mercaptohexadecyl) trimethylammonium bromide-modified cationic gold nanorods.  Biomaterials. 2018 Feb;154:275-290. doi: 10.1016/j.biomaterials.2017.10.044.

Durinikova, E., Kozovska, Z., Poturnajova, M., Plava, J., Cierna, Z., Babelova, A., Bohovic, R., Schmidtova, S., Tomas, M., Kucerova, L., Matuskova, M. (2018). ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells. BMC cancer, 18(1), 1-15. doi: 10.1186/s12885-018-4758-y.

Hricovíniová, Z., Hricovíni, M., Kozics, K. (2018). New series of quinazolinone derived Schiff’s bases: synthesis, spectroscopic properties and evaluation of their antioxidant and cytotoxic activity. Chemical Papers, 72(4), 1041-1053. doi: 10.1007/s11696-017-0345-y.

2017

Gábelová A, El Yamani N, Alonso TI, Buliaková B, Srančíková A, Bábelová A, Pran ER, Fjellsbø LM, Elje E, Yazdani M, Silva MJ, Dušinská M. Fibrous shape underlies the mutagenic and carcinogenic potential of nanosilver while surface chemistry affects the biosafety of iron oxide nanoparticles. Mutagenesis. 2017 Jan;32(1):193-202. doi: 10.1093/mutage/gew045.

Némethová, V., Buliaková, B., Mazancová, P., Bábelová, A., Šelc, M., Moravčíková, D., Klescikova, L., Ursinyova, M., Gabelova, A., Rázga, F. (2017). Intracellular uptake of magnetite nanoparticles: A focus on physico-chemical characterization and interpretation of in vitro data. Materials Science and Engineering: C, 70, 161-168. doi: 10.1016/j.msec.2016.08.064.

Smolkova, B., Dusinska, M., & Gabelova, A. (2017). Nanomedicine and epigenome. Possible health risks. Food and Chemical Toxicology, 109, 780-796. doi: 10.1016/j.fct.2017.07.020.

Buliaková B, Mesárošová M, Bábelová A, Šelc M, Némethová V, Šebová L, Rázga F, Ursínyová M, Chalupa I, Gábelová A. Surface-modified magnetite nanoparticles act  as aneugen-like spindle poison. Nanomedicine. 2017 Jan;13(1):69-80. doi: 10.1016/j.nano.2016.08.027.

Puškárová, A., Bučková, M., Kraková, L., Pangallo, D., Kozics, K. (2017). The antibacterial and antifungal activity of six essential oils and their cyto/genotoxicity to human HEL 12469 cells. Scientific reports, 7(1), 1-11. doi: 10.1038/s41598-017-08673-9.

Kosik, P., Skorvaga, M., Durdik, M., Jakl, L., Nikitina, E., Markova, E., Kozics, K., Horvathova, E., Belyaev, I. (2017). Low numbers of pre-leukemic fusion genes are frequently present in umbilical cord blood without affecting DNA damage response. Oncotarget, 8(22), 35824. doi: 10.18632/oncotarget.16211.

Imreova, P., Feruszova, J., Kyzek, S., Bodnarova, K., Zduriencikova, M., Kozics, K., Mucaji, P., Galova, E., Sevcovicova, A., Miadokova, E.,& Chalupa, I. (2017). Hyperforin exhibits antigenotoxic activity on human and bacterial cells. Molecules, 22(1), 167.

Kozics, K., Srancikova, A., Sedlackova, E., Horvathova, E., Melusova, M., Melds, V., Krajcovicova, Z., Sramkova, M. (2017). Antioxidant potential of essential oil from Lavandula angustifolia in in vitro and ex vivo cultured liver cells. Neoplasma, 64(4), 485-493. doi:10.4149/neo_2017_401.

2016

Horváthová, E., Srančíková, A., Regendová-Sedláčková, E., Melušová, M., Meluš, V., Netriová, J., Krajcovicova, Z., Slamenova, D., Pastorek, M., Kozics, K. (2016). Enriching the drinking water of rats with extracts of Salvia officinalis and Thymus vulgaris increases their resistance to oxidative stress. Mutagenesis, 31(1), 51-59. doi: 10.1093/mutage/gev056.

Leisegang, M. S., Babelova, A., Wong, M. S. K., Helfinger, V., Weißmann, N., Brandes, R. P., Schröder, K. (2016). The NADPH oxidase Nox2 mediates vitamin D-induced vascular regeneration in male mice. Endocrinology, 157(10), 4032-4040. doi: 10.1210/en.2016-1257.

Zarska, M., Novotny, F., Havel, F., Sramek, M., Babelova, A., Benada, O., Novotny, M., Saran, H., Kuca, K., Musilek, K., Hvezdova, Z., Dzijak, R., Vancurova, M., Krejcikova, K., Gabajova, B., Hanzlikova, H., Kyjacova, L., Bartek, J., Proska, J., Hodny, Z. (2016). Two-step mechanism of cellular uptake of cationic gold nanoparticles modified by (16-mercaptohexadecyl) trimethylammonium bromide. Bioconjugate chemistry, 27(10), 2558-2574. doi: 10.1021/acs.bioconjchem.6b00491.

2014

Mesárošová M, Kozics K, Bábelová A, Regendová E, Pastorek M, Vnuková D, Buliaková B, Rázga F, Gábelová A. The role of reactive oxygen species in the genotoxicity of surface-modified magnetite nanoparticles. Toxicol Lett. 2014 May  2;226(3):303-13. doi: 10.1016/j.toxlet.2014.02.025.

Goettsch C, Babelova A, Trummer O, Erben RG, Rauner M, Rammelt S, Weissmann N, Weinberger V, Benkhoff S, Kampschulte M, Obermayer-Pietsch B, Hofbauer LC, Brandes RP, Schröder K. NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis. J Clin Invest. 2013 Nov;123(11):4731-8.

Mieth A, Revermann M, Babelova A, Weigert A, Schermuly RT, Brandes RP. L-type calcium channel inhibitor diltiazem prevents aneurysm formation by blood pressure-independent anti-inflammatory effects. Hypertension. 2013 Dec;62(6):1098-104. doi: 10.1161/HYPERTENSIONAHA.113.01986.

Sturza A, Leisegang MS, Babelova A, Schröder K, Benkhoff S, Loot AE, Fleming I, Schulz R, Muntean DM, Brandes RP. Monoamine oxidases are mediators of endothelial dysfunction in the mouse aorta. Hypertension. 2013 Jul;62(1):140-6. doi: 10.1161/HYPERTENSIONAHA.113.01314.