Research Focus
Cell signaling is a very complex process used by cells to communicate with each other and ensure the coordination of all reactions in the body. Calcium ions are important signaling molecules that regulate important metabolic pathways not only in physiological but also in pathophysiological conditions. Calcium ions can enter cells from the external environment, but also from intracellular stores. The transport of calcium by different transport systems to specific locations at different times determines the specificity of calcium signaling. Therefore, one of the basic directions of the research group is to investigate the role of selected calcium transport systems in tumor cells, mainly in cells of renal cell carcinoma, ovarian carcinoma, and colorectal carcinoma.
An important part of the research is also the study of the role of adrenergic regulation in tumors and the possibility of using adrenergic receptor blockers in combination therapy for breast tumors and pancreatic tumors.
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Head of the Research Group
Prof. Oľga Križanová researches calcium and adrenergic signaling in tumor cells. She has completed stays in the USA, France, Germany, and Russia. She is a member of the Slovak Learned Society, has 210 publications, 4,742 citations according to WOS, 6,165 citations according to Google Scholar, and a Hirsch index of 31 (WOS) and 37 (Google Scholar).
Employees
| Title | Name | Phone | ORCID | |
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| Mgr. | ||||
| Mgr. | ||||
| B.Sc., PhD. |
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| prof. Ing., DrSc. | 02/ 3229 5312 |
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| Mgr., PhD. | 02/ 3229 5314 | |||
| 02/ 3229 5313 |